HPDB: Human Pigmentation Database
FAQs


Sl. No. Reference Journal Publication Year Allele Population Sub Population Gene SNP Amino Acid Change Trait Discovery OR (95% CI) Replication 1 OR (95% CI) Replication 2 OR (95% CI) p-Value Chromosome Variant location Variant Type
46 Abe et al. Journal of Dermatological Science 2013 G>C Asian Japanese SLC45A2 rs11568737 Thr500Pro Skin color NA NA NA NA 5 Exonic Missence
Journal of Dermatological Science A>C Asian Japanese SLC45A2 rs3733808 Val507Leu Skin color NA NA NA NA 5 Exonic Missence
Journal of Dermatological Science C>A,G Asian Japanese SLC45A2 rs16891982 His615Arg Skin color NA NA NA NA 5 Exonic Missence
Journal of Dermatological Science G>A Asian Japanese SLC45A2 rs26722 Glu272Lys Skin color NA NA NA NA 5 Intronic NA
Journal of Dermatological Science G>T Asian Japanese TYR rs13312741 Asp125Tyr Skin color NA NA NA NA 11 Exonic Missence
Journal of Dermatological Science T>A,C Asian Japanese OCA2 rs1800414 His615Arg Skin color NA NA NA 5.72E-06 15 Exonic Missence
Journal of Dermatological Science G>A Asian Japanese OCA2 rs74653330 Ala481Thr Skin color NA NA NA 6.18E--8 15 Exonic Missence
Journal of Dermatological Science C>T Asian Japanese OCA2 rs150335311 Thr387Met Skin color NA NA NA NA 15 Intronic NA
Journal of Dermatological Science G>A Asian Japanese MC1R rs34090186 Arg67Gln Skin color NA NA NA NA 16 Exonic NA
Journal of Dermatological Science G>A,C Asian Japanese MC1R rs2228479 Val92Met Skin color NA NA NA NA 16 Exonic NA
Journal of Dermatological Science T>C Asian Japanese MC1R rs33932559 His615Arg Skin color NA NA NA NA 16 Exonic NA
Journal of Dermatological Science G>A Asian Japanese MC1R rs885479 Arg163Gln Skin color NA NA NA NA 16 Exonic NA
47 Ruiz et al. Forensic Science International: Genetics 2013 A>G European European ASIP rs1015362 NA Eye color NA NA NA NA 20 NA NA
Forensic Science International: Genetics C>A European European HERC2 rs7183877 NA Eye color NA NA NA NA 15 Intronic NA
Forensic Science International: Genetics C>T European European TYRP1 rs1408799 NA Eye color NA NA NA NA 9 NA NA
Forensic Science International: Genetics G>A European European TYR rs1393350 NA Eye color NA NA NA NA 11 Intronic NA
Forensic Science International: Genetics C>A,G,T European European OCA2 rs4778232 NA Eye color NA NA NA NA 15 Intronic NA
Forensic Science International: Genetics C>T European European OCA2 rs8024968 NA Eye color NA NA NA NA 15 Intronic NA
Forensic Science International: Genetics C>T European European OCA2 rs1800407 Arg419Gln Eye color NA NA NA NA 15 Exonic Missence
Forensic Science International: Genetics C>T European European HERC2 rs1129038 NA Eye color NA NA NA NA 15 3 prime UTR NA
Forensic Science International: Genetics A>G European European ASIP rs6058017 NA Eye color NA NA NA NA 20 Intronic NA
Forensic Science International: Genetics C>T European European OCA2 rs1375164 NA Eye color NA NA NA NA 15 Intronic NA
Forensic Science International: Genetics C>A European European TYRP1 rs683 NA Eye color NA NA NA NA 9 Intronic NA
48 Praetorius et al. Cell Press 2013 C>T European Icelandic IRF4 rs12203592 NA Eye, Hair color NA NA NA NA 6 Intronic NA
Cell Press NA European Icelandic IRF4 rs872701 NA Eye, Hair color NA NA NA NA 6 Intronic NA
49 Wilde et al. PNAS 2014 C>G European European SLC45A2 rs16891982 Leu374Phe Skin, Hair, Eye color NA NA NA NA 5 Exonic Missence
PNAS A>G European European HERC2 rs12913832 NA Eye color NA NA NA NA 15 Intronic NA
PNAS C>A European European TYR rs1042602 Ser192Tyr Eye, Skin color NA NA NA NA 11 Exonic NA
50 Visser et al. Human Molecular Genetics 2014 G>A,C,T Asian East Asian BNC2 rs10756819 NA Skin color NA NA NA NA 9 Intronic NA
Human Molecular Genetics C>G,T Asian East Asian BNC2 rs2153271 NA Skin color NA NA NA NA 9 Intronic NA
Human Molecular Genetics G>A Asian East Asian HERC2 rs12913832 NA Skin color NA NA NA NA 15 Intronic NA
Human Molecular Genetics G>A,C Asian East Asian IRF4 rs12205392 NA Skin color NA NA NA NA 6 Intronic NA
Human Molecular Genetics T>A,G European European BNC2 rs10810657 NA Skin color NA NA NA NA 9 NA NA
Human Molecular Genetics G>A,C,T European European BNC2 rs12350739 NA Skin color NA NA NA NA 9 NA NA

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