HPDB: Human Pigmentation Database
FAQs


Sl no Reference Journal Publication year Allele Population Sub populations Gene SNP Amino acid change Trait Discovery OR (95% CI) Replication 1 OR (95% CI) Replication 2 OR (95% CI) p value Chromosome Functional Consequence
16 Yuasa et al. Biochemical genetics 2007 NA Asian Eurasia MC1R NA R163Q Skin color NA NA NA NA 16 NA
NA Asian Eurasia OCA2 NA H615R Skin color NA NA NA NA 15 NA
17 Han et al. Plos Genetics 2008 G>A European European HERC2 rs12913832 NA Hair color NA NA NA NA 15 Intragenic
G>A European European HERC2 rs1667394 NA Hair color NA NA NA NA 15 Intragenic
C>T European European HERC2 rs8039195 NA Hair color NA NA NA NA 15 Intragenic
C>T European European HERC2 rs11636232 NA Hair color NA NA NA NA 15 Intragenic
C>A European European HERC2 rs7183877 NA Hair color NA NA NA NA 15 Intragenic
T>G European European HERC2 rs1635168 NA Hair color NA NA NA NA 15 Intragenic
T>C European European HERC2 rs8028689 NA Hair color NA NA NA NA 15 Intragenic
G>A European European HERC2 rs16950987 NA Hair color NA NA NA NA 15 Intragenic
C > T European European IRF4 rs12203592 NA Hair color NA NA NA NA 6 Intragenic
A>G,T European European MC1R rs258322 NA Hair color NA NA NA NA 16 Intragenic
A>C,T European European MC1R rs4785763 NA Hair color NA NA NA NA 16 Intragenic
G>A European European MC1R rs8049897 NA Hair color NA NA NA NA 16 Intragenic
G>C,T European European MC1R rs4238833 NA Hair color NA NA NA NA 16 Intragenic
C >G,T European European MC1R rs4408545 NA Hair color NA NA NA NA 16 Intragenic
C >G,T European European MC1R rs7204478 NA Hair color NA NA NA NA 16 Intragenic
T>A,C,G European European MC1R rs7196459 NA Hair color NA NA NA NA 16 Intragenic
A>G,T European European MC1R rs164741 NA Hair color NA NA NA NA 16 Intragenic
G>A European European MC1R rs7188458 NA Hair color NA NA NA NA 16 Intragenic
C>T European European MC1R rs2353033 NA Hair color NA NA NA NA 16 Intragenic
C>T European European MC1R rs7195066 G809D Hair color NA NA NA NA 16 Intragenic
G>A,C European European MC1R rs2241039 NA Hair color NA NA NA NA 16 Intragenic
A>C European European OCA2 rs6497268 NA Hair color NA NA NA NA 15 Intragenic
A>C,G,T European European OCA2 rs11855019 NA Hair color NA NA NA NA 15 Intragenic
G>A,C,T European European OCA2 rs7174027 NA Hair color NA NA NA NA 15 Intragenic
A>G,T European European OCA2 rs7495174 NA Hair color NA NA NA NA 15 Intragenic
A>C European European OCA2 rs4778211 NA Hair color NA NA NA NA 15 Intragenic
G > T European European SLC24A4 rs12896399 NA Hair color NA NA NA NA 14 Intragenic
T>C European European MATP rs35391 NA Hair color NA NA NA NA 5 Intragenic
C>A European European MATP rs28777 NA Hair color NA NA NA NA 5 Intragenic
T>C European European KIF26A rs8007923 NA Hair color NA NA NA NA 14 NA
G>A,C European European EXOC2 rs9392056 NA Hair color NA NA NA NA 6 Intragenic
G>A,C,T European European EXOC2 rs2493040 NA Hair color NA NA NA NA 6 Intragenic
A>G European European EXOC2 rs6918152 NA Hair color NA NA NA NA 6 Intragenic
T>C,G European European OBSCN rs12142165 NA Hair color NA NA NA NA 1 Intragenic
18 Alonso et al. BMC Evolutionary Biology 2008 T>A Others Others TYRP1 rs13293905 NA Skin color NA NA NA NA 9 NA
T>G Others Others TYRP1 rs10756393 NA Skin color NA NA NA NA 9 Upstream
T>C,G Others Others TYRP1 rs2762462 NA Skin color NA NA NA NA 9 Downstream
A>C,G,T Others Others TYRP1 rs2762463 NA Skin color NA NA NA NA 9 Intragenic
C>A,G,T Others Others TYRP1 rs2733832 NA Skin color NA NA NA NA 9 Downstream
T>G Others Others TYRP1 rs2733833 NA Skin color NA NA NA NA 9 Downstream
C>A Others Others TYRP1 rs2075509 NA Skin color NA NA NA NA 9 Intragenic
T>C Others Others TYRP1 rs2209277 NA Skin color NA NA NA NA 9 Intragenic
C>A Others Others TYRP1 rs683 NA Skin color NA NA NA NA 9 Intragenic
A>T Others Others TYRP1 rs2762464 NA Skin color NA NA NA NA 9 Intragenic
A>C,G,T Others Others TYRP1 rs910 NA Skin color NA NA NA NA 9 Intragenic
T>A,C Others Others TYRP1 rs1063380 NA Skin color NA NA NA NA 9 Intragenic
G>A Others Others TYRP1 rs2733835 NA Skin color NA NA NA NA 9 NA
G>A Others Others TYRP1 rs12379024 NA Skin color NA NA NA NA 9 Intragenic
A>G Others Others TYRP1 rs10491744 NA Skin color NA NA NA NA 9 Intragenic
C>A,G,T Others Others DCT rs1325611 NA Skin color NA NA NA NA 13 Intragenic
T>A,C,G Others Others DCT rs1407995 NA Skin color NA NA NA NA 13 Intragenic
A>C,G,T Others Others DCT rs2031526 NA Skin color NA NA NA NA 13 Intragenic
C>G,T Others Others DCT rs3782972 NA Skin color NA NA NA NA 13 Intragenic
A>G Others Others DCT rs6492706 NA Skin color NA NA NA NA 13 Intragenic
T>C Others Others DCT rs9516418 NA Skin color NA NA NA NA 13 Intragenic
C>T Others Others DCT rs9584234 NA Skin color NA NA NA NA 13 Intragenic
G>A Others Others DCT rs12877248 NA Skin color NA NA NA NA 13 NA
G>A,C,T Others Others TYRP1 rs10809814 NA Skin color NA NA NA NA 9 NA
G>A,C Others Others TYRP1 rs4741242 NA Skin color NA NA NA NA 9 NA
T>C Others Others TYRP1 rs10960751 NA Skin color NA NA NA NA 9 NA
G>A Others Others TYRP1 rs10960752 NA Skin color NA NA NA NA 9 NA
G>A,C Others Others TYRP1 rs932761 NA Skin color NA NA NA NA 9 NA
19 Eiberg et al. Human genetics 2008 G>A European Danish HERC2 rs12913832 NA Eye color NA NA NA NA 15 Intragenic
C>T European Danish HERC2 rs1129038 NA Eye color NA NA NA NA 15 3 prime UTR
T>A,C,G European Danish OCA2 rs4778190 NA Eye color NA NA NA NA 15 Intragenic
G>A European Danish OCA2 rs1800401 R305W Eye color NA NA NA NA 15 Intragenic
A>C European Danish OCA2 rs4778241 NA Eye color NA NA NA NA 15 Intragenic
T>C European Danish HERC2 rs3935591 NA Eye color NA NA NA NA 15 Intragenic
A>G European Danish HERC2 rs2238289 NA Eye color NA NA NA NA 15 Intragenic
T>A European Danish HERC2 rs7170852 NA Eye color NA NA NA NA 15 Intragenic
C>T European Danish HERC2 rs11636232 NA Eye color NA NA NA NA 15 Intragenic
20 Kayser et al. Am J of Hum Gen. 2008 T>C,G European Netherland HERC2 rs916977 NA Eye color NA NA NA NA 15 Intragenic

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