Hypo2 - A Database of Hypothetical Proteins in Human

What is Hypo?

  • Hypo is a resource of hypothetical-proteins and pseudogenes and the current version is now complemented with predicting pseudogenes across eukaryotes


  • Hypothetical proteins are coded by orphan genes. Eventually, many of them turn out to be pseudogenes. In other words, the hypothetical proteins are the predecessors of pseudogenes

Why the webserver?

  • The known unknown regions are increasing in number, existing entries go in for rapid curations and citations.

  • It is developed as an integrated system to predict whether or not the candidate genes remain known unknowns or as pseudogenes

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